Invitrogen™ ASCC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550623

Catalog No. PA550623

Description

The antibody detects endogenous levels of total ASCC2 protein.

Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). [UniProt].

Specifications

• Antigen: ASCC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ASCC2
• Gene Alias: 1700011I11Rik; 2610034L15Rik; activating signal cointegrator 1 complex subunit 2; AI482016; ASC-1 complex subunit P100; Asc1p100; ASCC2; AW046480; p100; RGD1561422; trip4 complex subunit p100
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 75452, 84164
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 2.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q91WR3, Q9H1I8
• Gene Symbols: ASCC2
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human activating signal cointegrator 1 complex subunit 2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG