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Invitrogen™ ASGR1 Monoclonal Antibody (02)
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Catalog No. PIMA529043
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100 μL
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PIMA529043 100 μL
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Catalog No. PIMA529043 Supplier Invitrogen™ Supplier No. MA529043
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human ASGPR1.

The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASGR1
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 02
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Asgr1
Gene Accession No. P07306
Gene Alias ASGPR; ASGPR 1; ASGP-R 1; ASGPR1; ASGR; ASGR1; Asgr-1; asialoglycoprotein receptor (RHL1); asialoglycoprotein receptor 1; Asialoglycoprotein receptor 1 (hepatic lectin); asialoglycoprotein receptor RHL1; CLEC4H1; C-type lectin domain family 4 member H1; Hepatic lectin 1; hepatic lectin 1 RHL1; hepatic lectin 1, RHL1; hepatic lectin H1; HL-1; RATRHL1; RHL1; RHL-1; Unknown (protein for MGC:133691)
Gene Symbols Asgr1
Host Species Mouse
Immunogen Recombinant Human ASGPR1 Protein (Gln62-Leu291).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 432
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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