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ASH2 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501556924
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Quantity:
100 μL
Catalog No. Quantity
50-155-6924 100 μL
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Catalog No. 50-155-6924

Supplier: Bethyl Laboratories, Inc A300112A

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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia.

Specifications

Antigen ASH2
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene ASH2L
Gene Accession No. Q91X20, Q9UBL3
Gene Alias ASH2, ASH2L1, ASH2L2, Bre2, ASH2-like protein, set1/Ash2 histone methyltransferase complex subunit ASH2
Gene Symbols ASH2L
Host Species Rabbit
Immunogen Between 225 and 275
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23808, 9070
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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