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ASH2L Mouse anti-Human, Clone: OTI7D11, liquid, TrueMAB™
SDP

Catalog No. 501683753
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100 μL
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50-168-3753 100 μL
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Catalog No. 50-168-3753 Supplier OriGene Supplier No. TA810989
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Description

Mouse Monoclonal Antibody

Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia.

Specifications

Antigen ASH2L
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI7D11
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene ASH2L
Gene Accession No. Q9UBL3
Gene Alias ASH2, ASH2L1, ASH2L2, Bre2
Gene Symbols ASH2L
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 347-628 of human ASH2L produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9070
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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