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Invitrogen™ ASIC2 Polyclonal Antibody
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Catalog No. PIPA587945
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100 μL
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PIPA587945 100 μL
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Catalog No. PIPA587945 Supplier Invitrogen™ Supplier No. PA587945
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NLQIPDPHLA DPSVLEALRQ KANFKHYKPK QFSMLEFLHR VGHDLKDMML YCKFKGQECG HQDFTTVFTK YGKCYMFNSG EDGKPLLTTV KGGTGNGLEI MLDIQQDEYL PIWGETEETT FEAGVKVQIH SQSEPPFIQE LGFGVAPGFQ TFVATQEQRL TYLPPPWGEC RSSEMGLDFF PVYSITACRI DCETRYIVEN CNCRMVHMPG DAPFCTPEQH KECAEPALGL LAEKDSNYCL CRTPCNLTRY NKELSMVKIP SKTSAKYLEK KFNKSEKYIS E; Positive Samples: U-251MG, 293T, Mouse brain, Rat brain, Rat lung; Cellular Location: Cell membrane, Multi-pass membrane protein.

ACCN1 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this protein may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASIC2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 5.58 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ASIC2
Gene Accession No. Q16515, Q62962, Q925H0
Gene Alias ACCN; ACCN1; ACIC2; acid sensing (proton gated) ion channel 2; acid sensing ion channel 2; acid sensing ion channel subunit 2; acid-sensing (proton-gated) ion channel 2; acid-sensing ion channel 2; Amiloride-sensitive brain sodium channel; amiloride-sensitive brain sodium channel 2; Amiloride-sensitive cation channel 1, neuronal; amiloride-sensitive cation channel 1, neuronal (degenerin); Amiloride-sensitive cation channel neuronal 1; Asic2; ASIC2a; Bnac1; BNaC1a; BNC1; BNC1k; Brain sodium channel 1; degenerin; hBNaC1; Mammalian degenerin homolog; MDEG; MDEG1; MDEG2; neuronal amiloride-sensitive cation channel 1
Gene Symbols ASIC2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human ASIC2 (NP_0010852).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11418, 25364, 40
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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