Invitrogen™ ASIC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113613

Catalog No. PIPA5113613

Description

Immunogen sequence: LLDLLGKEED EGSHDENVST CDTMPNHSET ISHTVNVPLQ TTLGTLEEIA For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%.

ACCN1 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this protein may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.

Specifications

• Antigen: ASIC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ASIC2
• Gene Alias: ACCN; ACCN1; ACIC2; acid sensing (proton gated) ion channel 2; acid sensing ion channel 2; acid sensing ion channel subunit 2; acid-sensing (proton-gated) ion channel 2; acid-sensing ion channel 2; Amiloride-sensitive brain sodium channel; amiloride-sensitive brain sodium channel 2; Amiloride-sensitive cation channel 1, neuronal; amiloride-sensitive cation channel 1, neuronal (degenerin); Amiloride-sensitive cation channel neuronal 1; Asic2; ASIC2a; Bnac1; BNaC1a; BNC1; BNC1k; Brain sodium channel 1; degenerin; hBNaC1; Mammalian degenerin homolog; MDEG; MDEG1; MDEG2; neuronal amiloride-sensitive cation channel 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 40
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q16515
• Gene Symbols: ASIC2
• Immunogen: Synthetic peptide directed towards the middle region of human ACCN1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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