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Invitrogen™ ASIC3 Polyclonal Antibody
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Catalog No. PIPA127981
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50 μL
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PIPA127981 50 μL
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Catalog No. PIPA127981 Supplier Invitrogen™ Supplier No. PA127981
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Guinea Pig Polyclonal Antibody

Recommended positive controls: ASIC3 transfected cells and primary neuronal cells.

ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASIC3
Applications Immunohistochemistry (Frozen), Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with no preservative
Gene ASIC3
Gene Accession No. O35240, Q9UHC3
Gene Alias ACCN3; acid sensing (proton gated) ion channel 3; acid sensing ion channel 3; acid sensing ion channel subunit 3; acid-sensing (proton-gated) ion channel 3; acid-sensing ion channel 3; Amiloride-sensitive cation channel 3; amiloride-sensitive cation channel 3, testis; Asic3; AW742291; dorsal root ASIC; DRASIC; hASIC3; hTNaC1; modulatory subunit of ASIC2a; neuronal amiloride-sensitive cation channel 3; proton gated cation channel DRASIC; proton-gated cation channel subunit; SLNAC1; Testis sodium channel 1; TNaC1
Gene Symbols ASIC3
Host Species Guinea Pig
Immunogen (C)TASLDPDDFDPEPSDPLGSP.
Purification Method Antigen affinity chromatography
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 286920, 9311
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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