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Invitrogen™ ASIC3 Polyclonal Antibody
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Catalog No. PIPA541022
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100 μL
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PIPA541022 100 μL
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Catalog No. PIPA541022 Supplier Invitrogen™ Supplier No. PA541022
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Rabbit Polyclonal Antibody

Peptide sequence: VATFLYQVAE RVRYYREFHH QTALDERESH RLIFPAVTLC NINPLRRSRL Sequence homology: Cow: 80%; Dog: 80%; Guinea Pig: 80%; Horse: 80%; Human: 100%; Mouse: 87%; Pig: 87%; Rabbit: 87%; Rat: 87%.

ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASIC3
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene ASIC3
Gene Accession No. Q9UHC3
Gene Alias ACCN3; acid sensing (proton gated) ion channel 3; acid sensing ion channel 3; acid sensing ion channel subunit 3; acid-sensing (proton-gated) ion channel 3; acid-sensing ion channel 3; Amiloride-sensitive cation channel 3; amiloride-sensitive cation channel 3, testis; Asic3; AW742291; dorsal root ASIC; DRASIC; hASIC3; hTNaC1; modulatory subunit of ASIC2a; neuronal amiloride-sensitive cation channel 3; proton gated cation channel DRASIC; proton-gated cation channel subunit; SLNAC1; Testis sodium channel 1; TNaC1
Gene Symbols ASIC3
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human ACCN3 (aa 53-102).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9311
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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