Invitrogen™ ASIC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578825

Catalog No. PIPA578825

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Brain Tissue, Rat Testis Tissue, U87 Cell, NEURO Cell, SMMC Cell. Flow: U937 cell.

ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.

Specifications

• Antigen: ASIC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ASIC3
• Gene Alias: ACCN3; acid sensing (proton gated) ion channel 3; acid sensing ion channel 3; acid sensing ion channel subunit 3; acid-sensing (proton-gated) ion channel 3; acid-sensing ion channel 3; Amiloride-sensitive cation channel 3; amiloride-sensitive cation channel 3, testis; Asic3; AW742291; dorsal root ASIC; DRASIC; hASIC3; hTNaC1; modulatory subunit of ASIC2a; neuronal amiloride-sensitive cation channel 3; proton gated cation channel DRASIC; proton-gated cation channel subunit; SLNAC1; Testis sodium channel 1; TNaC1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171209, 286920, 9311
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: O35240, Q6X1Y6, Q9UHC3
• Gene Symbols: ASIC3
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3 (56-73aa FLYQVAERVRYYREFHHQ).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG