ASIC3 Polyclonal Antibody, Invitrogen™

Guinea Pig Polyclonal Antibody

Supplier:  Thermo Scientific PA5111817

Catalog No. PIPA5111817

Description

Reconstitute antibody with 50 μL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Peptide sequence is: KPRSGLEEAQ RRQAS(C) Homology: Mouse - 14/15 amino acid residues identical; human - 11/15 amino acid residues identical.

ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.

Specifications

• Antigen: ASIC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ASIC3
• Gene Alias: ACCN3; Acid-sensing ion channel 3; Amiloride-sensitive cation channel 3; ASIC3; AW742291; BOS_4613; Dorsal root ASIC; Drasic; hASIC3; hTNaC1; Neuronal amiloride-sensitive cation channel 3; SLNAC1; Testis sodium channel 1; TNAC1
• Host Species: Guinea Pig
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171209, 286920
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O35240, Q6X1Y6
• Gene Symbols: ASIC3
• Immunogen: Peptide corresponding to amino acid residues 2-16 of rat ASIC3 (Intracellular, N-terminus)
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG