ASL/Argininosuccinate Lyase Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS12515R

Catalog No. 50-198-2299

Description

ASL encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: ASL/Argininosuccinate Lyase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ASL
• Gene Alias: 2510006M18Rik; argininosuccinase; Argininosuccinate lyase; Arginosuccinase; ASAL; ASL
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 435
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P04424
• Gene Symbols: ASL
• Immunogen: KLH conjugated synthetic peptide derived from human ASL/Argininosuccinate Lyase.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG