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ASPP1Rabbit anti-Human, Polyclonal, Rockland™
SDP

Catalog No. 501991914
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Catalog No. Quantity
50-199-1914 100 μg
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Catalog No. 50-199-1914 Supplier Rockland Immunochemicals Supplier No. 600401A18
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Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Directed against human ASPP1. Minimal reactivity occurs against ASPP2. A BLAST analysis was used to suggest cross-reactivity with ASPP1 from mouse based on a 92% homology with the immunizing sequence. Reactivity against homologues from other sources is not known.

This gene encodes a member of the ASPP family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

Specifications

Antigen ASPP1
Applications ELISA, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene PPP1R13B
Gene Accession No. Q96KQ4
Gene Alias AI449786; Apoptosis-stimulating of p53 protein 1; apoptosis-stimulating protein of p53, 1; Aspp1; AW545810; KIAA0771; p53BP2-like; p85; Ppp1r13b; Protein phosphatase 1 regulatory subunit 13B; protein phosphatase 1, regulatory (inhibitor) subunit 13B; protein phosphatase 1, regulatory subunit 13B; Tp53bp2; transformation related protein 53 binding protein 2; Trp53bp2; tumor protein p53 binding protein, 2; tumor protein p53-binding protein, 2
Gene Symbols PPP1R13B
Host Species Rabbit
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23368
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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