ASPP2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A300819A

Catalog No. 50-155-8528

Description

The recommended shelf life for this product is 1 year from date of receipt.

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Specifications

• Antigen: ASPP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TP53BP2
• Gene Alias: 53BP2, ASPP2, BBP, P53BP2, PPP1R13A, BCL2-binding protein; apoptosis-stimulating of p53 protein 2; apoptosis-stimulating protein of p53, 2; renal carcinoma antigen NY-REN-51; tumor suppressor p53-binding protein 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7159
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/ml
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q13625
• Gene Symbols: TP53BP2
• Immunogen: Between 425 and 475
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG