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Invitrogen™ ASXL1 Polyclonal Antibody
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Catalog No. PIPA571475
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400 μL
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PIPA571475 400 μL
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Catalog No. PIPA571475 Supplier Invitrogen™ Supplier No. PA571475
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Description

Rabbit Polyclonal Antibody

ASXL1 Polyclonal Antibody for Flow, ICC/IF, IHC (P), Western Blot

Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator of RARA and RXRA through association with NCOA1. Acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters. Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASXL1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Asxl1
Gene Accession No. P59598, Q8IXJ9
Gene Alias additional sex combs like 1; additional sex combs like 1, transcriptional regulator; additional sex combs like transcriptional regulator 1; additional sex combs-like protein 1; Asxl1; BOPS; KIAA0978; MDS; MGC117280; MGC71111; mKIAA0978; Polycomb group protein ASXL1; putative Polycomb group protein ASXL1; RGD1561878
Gene Symbols Asxl1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 521-549 amino acids from the Central region of human ASXL1.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171023, 228790
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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