Invitrogen™ ASXL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568361

Catalog No. PIPA568361

Description

ASXL2 Polyclonal Antibody for IHC (P)

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.

Specifications

• Antigen: ASXL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ASXL2
• Gene Alias: 4930556B16Rik; additional sex combs like 2; additional sex combs like 2 (Drosophila); additional sex combs like 2, transcriptional regulator; additional sex combs like transcriptional regulator 2; additional sex combs-like protein 2; ASXH2; ASXL transcriptional regulator 2; ASXL2; Kiaa1685; mKIAA1685; polycomb group protein ASXH2; polycomb group protein ASXH2 homolog; putative Polycomb group protein ASXL2
• Host Species: Rabbit
• Purification Method: affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55252
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.8 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q76L83
• Gene Symbols: ASXL2
• Immunogen: Synthetic protein corresponding to residues near the C terminal of human ASXL2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG