Invitrogen™ ASZ1 Monoclonal Antibody (3C9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524521

Catalog No. PIMA524521

Description

Peptide Sequence: QILKCVELLL SRNADPNVAC RRLMTPIMYA ARDGHTQVVA LLVAHGAEVN TQDENGYTAL TWAARQGHKN IVLKLLELGA NKMLQTKDGK MPSEIAKRNK HHEIFNLL.

Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

Specifications

• Antigen: ASZ1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: Asz1
• Gene Alias: 4933400N19Rik; ALP1; ANKL1; ankyrin repeat, SAM and basic leucine zipper domain containing 1; ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; ankyrin-like 1; ankyrin-like protein 1; Asz1; C7orf7; CT1.19; GASZ; germ cell-specific ankyrin, SAM and basic leucine zipper domain containing protein; germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein; Orf3
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 136991
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 3C9
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q8WWH4
• Gene Symbols: Asz1
• Immunogen: ASZ1 (NP_570124, 127 a.a. ~ 234 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ