Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Crosslinking, Labeling and Protein Modification
  5. Protein Labeling Reagents
  6. Tocris Bioscience™ AT 101 Inhibitor

Tocris Bioscience™ AT 101 Inhibitor
SDP

Catalog No. NB336710MG Shop All R&D Systems Products
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
NB336710MG 10 mg
NB336750MG 50 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Catalog No. NB336710MG Supplier Tocris Bioscience™ Supplier No. NB336710MG

Description

Low molecular weight, organic compound that may help regulate biological process.

Biological Activity:
R-(-)-enantiomer of gossypol. Mimics BH3 domains of Bcl-2, Bcl-XL and Mcl-1. Disrupts heterodimerization of Bcl-2 with proapoptotic family members. Induces apoptosis in vitro through activation of caspase-9; cytotoxic to multiple myeloma and drug-resistant cell lines. Delays onset of androgen-independent growth of VCaP prostate cancer xenografts in vivo.

Storage: Store the unopened product at 2° to 8°C. Do not use past expiration date.

Specifications

Formulation C30H30O8
For Use With (Application) Inhibits apoptosis
Quantity 10 mg
Product Type Inhibits apoptosis
Molecular Weight (g/mol) 518.56g/mol
Solubility Soluble to 100mM in DMSO, 100mM in ethanol
Content And Storage -20°C
Target AT 101
Color Dark Purple

For Laboratory Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.