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Ataxin 2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 217761AP150UL

Description
The autosomal domit cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal domit cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. SCA2 is caused by expansion of a CAG repeat in the coding region of this gene. Longer expansions result in earlier onset of the disease. Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined.Specifications
Ataxin 2 | |
Polyclonal | |
Unconjugated | |
ATXN2 | |
ataxin 2, ATX2, ATXN2, SCA2, TNRC13 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
20239, 288663, 6311 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.25 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
O70305, Q99700 | |
Atxn2 | |
Ataxin 2 Fusion Protein Ag16470 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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