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Ataxin 7 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody
Supplier: Bioss BS11318R

Description
Spinocerebellar ataxia type 7 (SCA7) belongs to a class of hereditary neurodegenrative diseases characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem and causes dementia, macular degeneration and other neurodegenerative characteristics. SCA7 gene encodes the ubiquitous 892 residue protein ataxin-7. This protein is typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. In cells where there is a mutation of the SCA7 gene, ataxin 7 accumulates in intranuclear inclusions and can result in cell death.Specifications
Ataxin 7 | |
Polyclonal | |
Unconjugated | |
ATXN7 | |
A430107N12Rik; ADCAII; AI627028; ataxin 7; Ataxin-7; Atxn7; Atxn7-PA; Atxn7-PB; Atxn7-PC; Atxn7-PD; CG9866; CG9866 gene product from transcript CG9866-RA; CG9866-PA; CG9866-PB; CG9866-PC; CG9866-PD; Dmel\CG9866; Dmel_CG9866; OPCA3; RGD1562692; SCA7; spinocerebellar ataxia 7 homolog; Spinocerebellar ataxia type 7 protein; Spinocerebellar ataxia type 7 protein homolog | |
Rabbit | |
Protein A | |
RUO | |
6314 | |
-20°C | |
Liquid |
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
1 μg/mL | |
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH | |
O15265 | |
ATXN7 | |
KLH conjugated synthetic peptide derived from human Ataxin 7. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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