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Ataxin 7 Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS11318R

Encompass_Preferred

Catalog No. 50-198-1263


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Description

Description

Spinocerebellar ataxia type 7 (SCA7) belongs to a class of hereditary neurodegenrative diseases characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem and causes dementia, macular degeneration and other neurodegenerative characteristics. SCA7 gene encodes the ubiquitous 892 residue protein ataxin-7. This protein is typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. In cells where there is a mutation of the SCA7 gene, ataxin 7 accumulates in intranuclear inclusions and can result in cell death.
Specifications

Specifications

Ataxin 7
Polyclonal
Unconjugated
ATXN7
A430107N12Rik; ADCAII; AI627028; ataxin 7; Ataxin-7; Atxn7; Atxn7-PA; Atxn7-PB; Atxn7-PC; Atxn7-PD; CG9866; CG9866 gene product from transcript CG9866-RA; CG9866-PA; CG9866-PB; CG9866-PC; CG9866-PD; Dmel\CG9866; Dmel_CG9866; OPCA3; RGD1562692; SCA7; spinocerebellar ataxia 7 homolog; Spinocerebellar ataxia type 7 protein; Spinocerebellar ataxia type 7 protein homolog
Rabbit
Protein A
RUO
6314
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
O15265
ATXN7
KLH conjugated synthetic peptide derived from human Ataxin 7.
100 μL
Primary
Human
Antibody
IgG
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