Ataxin 7 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-1263	100 μL

Catalog No. 50-198-1263 Supplier Bioss Supplier No. BS11318R

Description

Rabbit Polyclonal Antibody

Spinocerebellar ataxia type 7 (SCA7) belongs to a class of hereditary neurodegenrative diseases characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem and causes dementia, macular degeneration and other neurodegenerative characteristics. SCA7 gene encodes the ubiquitous 892 residue protein ataxin-7. This protein is typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. In cells where there is a mutation of the SCA7 gene, ataxin 7 accumulates in intranuclear inclusions and can result in cell death.

Specifications

• Antigen: Ataxin 7
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ATXN7
• Gene Accession No.: O15265
• Gene Alias: A430107N12Rik; ADCAII; AI627028; ataxin 7; Ataxin-7; Atxn7; Atxn7-PA; Atxn7-PB; Atxn7-PC; Atxn7-PD; CG9866; CG9866 gene product from transcript CG9866-RA; CG9866-PA; CG9866-PB; CG9866-PC; CG9866-PD; Dmel\CG9866; Dmel_CG9866; OPCA3; RGD1562692; SCA7; spinocerebellar ataxia 7 homolog; Spinocerebellar ataxia type 7 protein; Spinocerebellar ataxia type 7 protein homolog
• Gene Symbols: ATXN7
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Ataxin 7.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6314
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG