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Invitrogen™ ATF1 Monoclonal Antibody (ATF1 2A9/8)
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Catalog No. MA121313
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Quantity:
100 μg
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Catalog No. Quantity
MA121313 100 μg
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Catalog No. MA121313 Supplier Invitrogen™ Supplier No. MA121313
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Description

Mouse Monoclonal Antibody

The predicted molecular weight of MA1-21313 is 60 kDa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATF1
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone ATF1 2A9/8
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2
Gene ATF1
Gene Accession No. P18846
Gene Alias AATase 1; Activating transcription factor 1; alcohol O-acetyltransferase; Alcohol O-acetyltransferase 1; ATF1; Atf-1; cAMP-dependent transcription factor ATF-1; cyclic AMP-dependent transcription factor ATF-1; EWS-ATF1; FUS/ATF-1; Protein TREB36; TCR-ATF1; TREB36; Unknown (protein for MGC:64099); wu:fc92c07; YOR377W; zgc:64099
Gene Symbols ATF1
Host Species Mouse
Immunogen ATF1.
Purification Method IgG fraction
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 466
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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