Invitrogen™ ATF3 Monoclonal Antibody (5A9B9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531634

Catalog No. PIMA531634

Description

MA5-31634 has been tested in indirect ELISA.

ATF3 (Activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: ATF3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P18847
• Gene Symbols: ATF3
• Immunogen: Purified recombinant fragment of human ATF3 (AA: 1-181) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 5A9B9
• Conjugate: Unconjugated
• Gene: ATF3
• Gene Alias: activating transcription factor 3; ATF 3; ATF3; cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; Liver regeneration factor 1; Lrf1; LRF-1; LRFI; LRG-21; MGC137608 protein; transcription factor LRG-21; zgc:55526
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 467
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid