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Invitrogen™ ATF3 Monoclonal Antibody (CL1685)
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Catalog No. PIMA531360
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100 μL
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Catalog No. Quantity
PIMA531360 100 μL
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Catalog No. PIMA531360 Supplier Invitrogen™ Supplier No. MA531360
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Description

Mouse Monoclonal Antibody

Immunogen sequence: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TEC Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 92%.

ATF3 (Activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATF3
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Monoclonal
Clone CL1685
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ATF3
Gene Accession No. P18847
Gene Alias activating transcription factor 3; ATF 3; ATF3; cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; Liver regeneration factor 1; Lrf1; LRF-1; LRFI; LRG-21; MGC137608 protein; transcription factor LRG-21; zgc:55526
Gene Symbols ATF3
Host Species Mouse
Immunogen Recombinant protein fragment of Human ATF3 (Product #RP-94772)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 467
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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