ATF3 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0326	100 μL

Catalog No. 50-198-0326 Supplier Bioss Supplier No. BS0519R

Description

Rabbit Polyclonal Antibody

ATF3 (Activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: ATF3
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ATF3
• Gene Accession No.: P18847
• Gene Alias: Activating transcription factor 3; ATF 3; ATF3; BOS_16130; cAMP-dependent transcription factor ATF-3; Cyclic AMP-dependent transcription factor ATF-3; Liver regeneration factor 1; LOC100337749; Lrf1; LRF-1; LRFI; LRG-21; Transcription factor LRG-21; zgc:55526
• Gene Symbols: ATF3
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human ATF3.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 467
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG