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ATF4 Mouse anti-Human, Clone:2A6F12, Abnova™

Catalog No. 89334338 Shop All Abnova Corporation Products
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89-334-338 100 μg
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Catalog No. 89-334-338 Supplier Abnova Corporation Supplier No. MAB17890
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Description

Mouse monoclonal antibody raised against partial recombinant human ATF4.

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. [provided by RefSeq]

Specifications

Antigen ATF4
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2A6F12
Conjugate Unconjugated
Description activating transcription factor 4 (tax-responsive enhancer element B67)
Dilution ELISA (1:10000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.
Formulation In PBS (0.05% sodium azide)
Gene ATF4
Gene Alias CREB-2, CREB2, TAXREB67, TXREB
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acids 212-351 of human ATF4.
Quantity 100 μg
Gene ID (Entrez) 468
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG1
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