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Invitrogen™ ATF7 Polyclonal Antibody
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Catalog No. PIPA5106473
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100 μL
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PIPA5106473 100 μL
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Catalog No. PIPA5106473 Supplier Invitrogen™ Supplier No. PA5106473
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ATF7.

Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATF7
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ATF7
Gene Accession No. P17544, Q8R0S1
Gene Alias 1110012F10Rik; 9430065F09Rik; activating transcription factor 7; AI549878; ATF7; ATFA; C130020M04Rik; cAMP-dependent transcription factor ATF-7; Cyclic AMP-dependent transcription factor ATF-7; MGC57182; transcription factor ATF-A
Gene Symbols ATF7
Host Species Rabbit
Immunogen A synthesized peptide derived from human ATF7(Accession P17544), corresponding to amino acid residues P54-P104.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11016, 223922, 315333
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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