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ATG1/ULK1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985524
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50-198-5524 100 μL
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Catalog No. 50-198-5524 Supplier Bioss Supplier No. BS3602R
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Description

Rabbit Polyclonal Antibody

ULK1, also known as ATG1, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK1 results in a severe defect in the autophagy pathway. ULK1 is highly conserved among eukaryotes, and are the Unc-51-like kinases, ULK1 and ULK2 in mammals. ULK1 is ubiquitously expressed and involved in autophagy in response to starvation. It is the target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13. ULK1 also plays a role early in neuronal differentiation.

Specifications

Antigen ATG1/ULK1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ULK1
Gene Accession No. O75385
Gene Alias APG1; ATG 1; ATG1; ATG1 autophagy related 1 homolog; ATG1A; AU041434; Autophagy-related protein 1 homolog; C. elegans; EC:2.7.11.1; FLJ38455; hATG1; KIAA0722; mKIAA0722; Serine/threonine-protein kinase ULK1; Serine/threonine-protein kinase Unc51.1; ULK 1; ULK1; UNC 51; UNC51; unc-51 like autophagy activating kinase 1; unc-51 like kinase 1; Unc51.1; Unc-51-like kinase 1
Gene Symbols ULK1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ATG1/ULK1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8408
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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