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Invitrogen™ ATG10 Polyclonal Antibody
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Catalog No. PIPA5111196
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100 μL
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PIPA5111196 100 μL
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Catalog No. PIPA5111196 Supplier Invitrogen™ Supplier No. PA5111196
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IGDSWEWRPS KDCSDGYMCK IHFQIKNGSV MSHLGASTHG QTCLPMEEAF ELPLDDCEVI ETAAASEVIK YEYHVLYSCS YQVPVLYFRA SFLDGRPLTL KDIWEGVHEC YKM Highest antigen sequence indentity to the following orthologs: Mouse - 70%, Rat - 68%.

ATG10 is involved in autophagy which is a process for the bulk degradation of cytosolic compartments by lysosomes/vacuoles. The formation of autophagosomes involves a dynamic rearrangement of the membrane for which two ubiquitin-like modifications (the conjugation of APG12p and the modification of a soluble form of MAP-LC3 to a membrane-bound form) are essential. APG10 is an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation, ATG12 -ATG5 conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A), a homolog of yeast Apg8, to a membrane-bound form. The protein ATG10 is ubiquitously expressed and the human APG10L gene is localized on chromosome 5q14.2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATG10
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ATG10
Gene Accession No. Q9H0Y0
Gene Alias 5330424L23Rik; 5430428K15Rik; Agp10; AI852123; APG10; APG10L; APG10-like; Apg10p; ATG10; ATG10 autophagy related 10 homolog; Atg10l; autophagy related 10; autophagy related 10 homolog; autophagy-related 10; autophagy-related protein 10; DKFZp586I0418; FLJ13954; mAPG10; pp12616; Ubiquitin-like-conjugating enzyme ATG10
Gene Symbols ATG10
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human ATG10. Recombinant protein control fragment (Product #RP-102958).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 83734
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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