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ATG3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985835
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50-198-5835 100 μL
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Catalog No. 50-198-5835 Supplier Bioss Supplier No. BS4013R
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Description

Rabbit Polyclonal Antibody

ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. Autophagy is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG3 functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy.

Specifications

Antigen ATG3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ATG3
Gene Accession No. Q9NT62
Gene Alias 2610016C12Rik; APG3; APG3L; APG3-like; Apg3p; atg3; ATG3 autophagy related 3 homolog; ATG3 autophagy related 3 homolog (S. cerevisiae); atg3.S; Atg3l; autophagy related 3; autophagy related 3 S homeolog; autophagy-related 3; Autophagy-related protein 3; BOS_748; DKFZp564M1178; FLJ22125; hApg3; MGC15201; PC3-96; Pig1; PIG-1; Preconditioning-inducible gene 1 protein; Protein PC3-96; Ubiquitin-like-conjugating enzyme ATG3; XELAEV_18014721mg
Gene Symbols ATG3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ATG3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64422
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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