Invitrogen™ ATG4A Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142407

Catalog No. PIPA5142407

Description

Additional Information: This antibody is expected to recognize both reported isoforms (NP_443168.2; NP_840054.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

Specifications

• Antigen: ATG4A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATG4A
• Gene Alias: AI627006; APG4 (ATG4) autophagy-related homolog A; APG4 autophagy 4 homolog A; APG4A; ATG4 autophagy related 4 homolog A; Atg4a; Atg4al; Atg4al1; AUTL2; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; autophagin 2; autophagin-2; autophagy 4 homolog A; autophagy related 4 homolog A; autophagy related 4A cysteine peptidase; autophagy related 4A, cysteine peptidase; autophagy related 4A, cysteine peptidase-like 1; autophagy-related 4A; autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; AV169859; cysteine protease APG4A; cysteine protease ATG4A; hAPG4A; MGC107179
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 115201
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8WYN0
• Gene Symbols: ATG4A
• Immunogen: Peptide with sequence TEENGTVNDQTFHC (aa 289-302).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG