Invitrogen™ ATG4A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5111588

Catalog No. PIPA5111588

Description

Immunogen sequence: ESVLSKYEDQ ITIFTDYLEE YPDTDELVWI LGKQHLLKTE KSKLLSDISA RLWFTYRRKF SPIGGTG.

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

Specifications

• Antigen: ATG4A
• Classification: Polyclonal
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8WYN0
• Gene Symbols: ATG4A
• Immunogen: Recombinant Protein corresonding to Human ATG4A. Recombinant protein control fragment (Product #RP-105342).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Gene: ATG4A
• Gene Alias: AI627006; APG4 (ATG4) autophagy-related homolog A; APG4 autophagy 4 homolog A; APG4A; ATG4 autophagy related 4 homolog A; Atg4a; Atg4al; Atg4al1; AUTL2; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; autophagin 2; autophagin-2; autophagy 4 homolog A; autophagy related 4 homolog A; autophagy related 4A cysteine peptidase; autophagy related 4A, cysteine peptidase; autophagy related 4A, cysteine peptidase-like 1; autophagy-related 4A; autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; AV169859; cysteine protease APG4A; cysteine protease ATG4A; hAPG4A; MGC107179
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115201
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid