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Atg4B Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501563760
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50-156-3760 100 μL
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Catalog No. 50-156-3760 Supplier Bethyl Laboratories, Inc Supplier No. A302898A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Cysteine protease ATG4b is an enzyme which is coded by ATG4b gene. Autophagy is a critical cellular homeostatic process that controls the turnover of damaged organelles and protein. ATG4bis a deubiquitin-like protease that plays dual roles in the core machinery of autophagy. ATG4b, cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. ATG4b is mainly expressed in the skeletal muscle, brain, heart, liver and pancreas.

Specifications

Antigen Atg4B
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene ATG4B
Gene Accession No. Q8BGE6, Q9Y4P1
Gene Alias Cysteine protease ATG4B, Autophagy-related protein 4 homolog B, hAPG4B, Autophagin-1, Autophagy-related cysteine endopeptidase 1, AUT-like 1 cysteine
Gene Symbols Atg4b
Host Species Rabbit
Immunogen Between 350 and 400
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23192, 66615
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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