Invitrogen™ ATG4D Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106650

Catalog No. PIPA5106650

Description

Antibody detects endogenous levels of total ATG4D.

Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid protein that localizes to the cytoplasm and belongs to the C-54 family of cysteine proteases. Expressed predominately in skeletal muscle, but also present in testis, Atg4D functions as a cysteine protease that is required for autophagy and functions to specifically cleave the C-terminal region of target proteins, thereby allowing the target proteins to bind to autophagosomes. The enzymatic activity of Atg4D is inhibited by Nethylmaleimide, a thiol reactive compound that is capable of modifying cystine residues in proteins and peptides.

Specifications

• Antigen: ATG4D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Atg4d
• Gene Alias: 9830134P12Rik; APG4 (ATG4) autophagy-related homolog D; APG4 autophagy 4 homolog D; APG4D; APG4-D; ATG4 autophagy related 4 homolog D; Atg4d; Atg4dl; Autl4; AUT-like 4 cysteine endopeptidase; AUT-like 4, cysteine endopeptidase; Autophagin-4; autophagy related 4D cysteine peptidase; autophagy related 4D, cysteine peptidase; autophagy-related 4D; autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; cysteine protease ATG4D; Cysteine protease ATG4D, mitochondrial; cysteine protease involved in autophagy; cysteine protease involved in autophagy APG4-D
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 235040, 84971
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q86TL0, Q8BGV9
• Gene Symbols: Atg4d
• Immunogen: A synthesized peptide derived from human ATG4D(Accession Q86TL0), corresponding to amino acid residues Y425-L474.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG