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Invitrogen™ ATG9A Monoclonal Antibody (14F2 8B1), Alexa Fluor™ 488
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Catalog No. PIMA1149A48
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50 μg
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PIMA1149A48 50 μg
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Catalog No. PIMA1149A48 Supplier Invitrogen™ Supplier No. MA1149A488
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Description

Armenian Hamster Monoclonal Antibody

MA1-149A-488 was produced in Armenian hamster and detects ATG9 in human, rat and mouse samples. In Immunofluorescence applications, MA1-149A488 shows accumulation and redistribution of ATG9 in response to starvation-induced autophagosome assembly.

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATG9A
Applications Immunocytochemistry
Classification Monoclonal
Clone 14F2 8B1
Concentration 1.0 mg/mL
Conjugate Alexa Fluor 488
Formulation PBS with 1.0mg/mL BSA and 0.05% sodium azide
Gene ATG9A
Gene Accession No. Q5FWU3, Q68FE2, Q7Z3C6
Gene Alias Apg9; APG9 autophagy 9-like 1; Apg911; APG9A; APG9L1; APG9-like 1; ATG 9A; Atg9; ATG9 autophagy related 9 homolog A; ATG9 autophagy related 9 homolog A (S. cerevisiae); Atg9a; Atg9l1; AU019532; autophagy 9-like 1 protein; autophagy protein 9; autophagy related 9A; autophagy-related 9A; autophagy-related 9-like 1; autophagy-related protein 9; autophagy-related protein 9A; FLJ22169; mATG9; MGD3208; RGD1310450; zgc:158700
Gene Symbols ATG9A
Host Species Armenian Hamster
Immunogen peptide sequence HPEPVPEEGSEDELPPQVHK of human ATG9A C-terminus.
Purification Method Protein A
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 245860, 363254, 79065
Target Species Human, Mouse, Rat
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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