Invitrogen™ ATG9A Recombinant Rabbit Monoclonal Antibody (SC67-05)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA532238

Catalog No. PIMA532238

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.

Specifications

• Antigen: ATG9A
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q5FWU3, Q68FE2, Q7Z3C6
• Gene Symbols: ATG9A
• Immunogen: Synthetic peptide within Human ATG9A aa 799-839.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Clone: SC67-05
• Conjugate: Unconjugated
• Gene: ATG9A
• Gene Alias: Apg9; APG9 autophagy 9-like 1; Apg911; APG9A; APG9L1; APG9-like 1; ATG 9A; Atg9; ATG9 autophagy related 9 homolog A; ATG9 autophagy related 9 homolog A (S. cerevisiae); Atg9a; Atg9l1; AU019532; autophagy 9-like 1 protein; autophagy protein 9; autophagy related 9A; autophagy-related 9A; autophagy-related 9-like 1; autophagy-related protein 9; autophagy-related protein 9A; FLJ22169; mATG9; MGD3208; RGD1310450; zgc:158700
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 245860, 363254, 79065
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid