Invitrogen™ ATL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120901

Catalog No. PIPA5120901

Description

Positive test controls include: SH-SY5Y, LOVO, H460, 293T, U-87MG, U-251MG, Mouse brain. The target is usually found in the following locations: Cell projection, Endoplasmic reticulum membrane, Golgi apparatus membrane, Multi-pass membrane protein, axon. Immunogen sequence: MAKNRRDRNS WGGFSEKTYE WSSEEEEPVK KAGPVQVLIV KDDHSFELDE TALNRILLSE AVRDKEVVAV SVAGAFRKGK SFLMDFMLRY MYNQESVDWV GDYNEPLTGF SWRGGSERET TGIQIWSEIF LINKPDGKKV AVLLMDTQGT FDSQSTLRDS ATVFALSTMI SSIQVYNLSQ NVQEDDLQHL QLFTEYGRLA MEETFLKPFQ SLIFLVRDWS FPYEFSYGAD GGAKFLEKRL KVSGNQHEEL QNVRKHIHSC FTNISCFLLP HPGLKVATNP.

The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: ATL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATL1
• Gene Alias: 4930435M24Rik; Adfsp; AD-FSP; ATL1; ATL1 alpha; ATL1 beta; ATL1 gamma; ATL1-delta; atlastin GTPase 1; atlastin1; atlastin-1; Bcl11B; BCL-11B; BCL11B/TRDC fusion; brain-specific GTP-binding protein; Ctip 2; CTIP2; CTIP-2; Fsp1; GBP3; GBP-3; GTP-binding protein 3; guanine nucleotide-binding protein 3; guanylate-binding protein 3; hGBP3; hRit1; hRIT1 alpha; HSN1D; Rit 1; Rit1; spastic paraplegia 3 protein A; Spastic paraplegia 3A homolog; SPG3; SPG3A; ZNF856B
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51062, 73991
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.97 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8BH66, Q8WXF7
• Gene Symbols: ATL1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ATL1 (NP_056999.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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