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Invitrogen™ ATMIN Polyclonal Antibody
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Catalog No. PIPA564295
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100 μL
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PIPA564295 100 μL
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Catalog No. PIPA564295 Supplier Invitrogen™ Supplier No. PA564295
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Rabbit Polyclonal Antibody

Immunogen sequence: TFRCTCGCPY ASRTALQSHI YRTGHEIPAE HRDPPSKKRK MENCAQNQKL SNKTIESLNN QPIPRPDTQE LEASEIKLEP SFEDSCGSNT D Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.

The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51. ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects. It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATMIN
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ATMIN
Gene Accession No. O43313
Gene Alias ASCIZ; ATM INteracting protein; ATM interactor; ATM/ATR-substrate CHEK2-interacting zinc finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein; ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein; atmin; gpg6; KIAA0431; mKIAA0431; RGD1305781; Zinc finger protein 822; ZNF822
Gene Symbols ATMIN
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ATMIN. Recombinant protein control fragment (Product #RP-103644).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23300
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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