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Invitrogen™ ATP11A Polyclonal Antibody
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Catalog No. PIPA520995
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100 μg
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PIPA520995 100 μg
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Catalog No. PIPA520995 Supplier Invitrogen™ Supplier No. PA520995
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Description

Rabbit Polyclonal Antibody

A suggested positive control is K562 cell lysate. PA5-20995 can be used with blocking peptide PEP-1109.

ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATP11A
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ATP11A
Gene Accession No. P98196, P98197
Gene Alias 4930558F19Rik; ATP11A; ATPase 11A, class VI; ATPase 11A, p type; ATPase class VI type 11A; ATPase IS; ATPase phospholipid transporting 11A; ATPase, class 1, member h; ATPase, class VI, type 11A; Atpc1h; ATPIH; ATPIS; AU040868; Ih; KIAA1021; P4-ATPase flippase complex alpha subunit ATP11A; phospholipid-translocating ATPase; potential phospholipid-transporting ATPase IH; probable phospholipid-transporting ATPase IH; RP11-120K24.1; Ua20
Gene Symbols ATP11A
Host Species Rabbit
Immunogen A 19 amino acid peptide near the amino terminus of human ATP11A.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23250, 306600, 50770
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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