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Invitrogen™ ATP11B Polyclonal Antibody
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Catalog No. PIPA557579
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100 μL
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PIPA557579 100 μL
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Catalog No. PIPA557579 Supplier Invitrogen™ Supplier No. PA557579
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ETAVSVSLSC GHFHRTMNIL ELINQKSDSE CAEQLRQLAR RITEDHVIQH GLVVDGTSLS LALREHEKLF MEVCRN Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATP11B
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ATP11B
Gene Accession No. Q9Y2G3
Gene Alias 1110019I14Rik; ATP11B; ATPase class VI type 11B; ATPase IR; ATPase phospholipid transporting 11B (putative); ATPase, class VI, type 11B; ATPIF; ATPIR; KIAA0956; mKIAA0956; P4-ATPase flippase complex alpha subunit ATP11B; Probable phospholipid-transporting ATPase IF; TIEG; TIEG1; truncated ATPase 11B protein
Gene Symbols ATP11B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ATP11B. Recombinant protein control fragment (Product #RP-96267).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23200
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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