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Invitrogen™ ATP11B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557579

Catalog No. PIPA557579


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Description

Description

Immunogen sequence: ETAVSVSLSC GHFHRTMNIL ELINQKSDSE CAEQLRQLAR RITEDHVIQH GLVVDGTSLS LALREHEKLF MEVCRN Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ATP11B
Polyclonal
Unconjugated
ATP11B
1110019I14Rik; ATP11B; ATPase class VI type 11B; ATPase IR; ATPase phospholipid transporting 11B (putative); ATPase, class VI, type 11B; ATPIF; ATPIR; KIAA0956; mKIAA0956; P4-ATPase flippase complex alpha subunit ATP11B; Probable phospholipid-transporting ATPase IF; TIEG; TIEG1; truncated ATPase 11B protein
Rabbit
Antigen Affinity Chromatography
RUO
23200
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9Y2G3
ATP11B
Recombinant protein corresponding to Human ATP11B. Recombinant protein control fragment (Product #RP-96267).
100 μL
Primary
Human
Antibody
IgG
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