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Invitrogen™ ATP2A1 Recombinant Rabbit Monoclonal Antibody (JE45-75)
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Catalog No. PIMA534844
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100 μL
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PIMA534844 100 μL
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Catalog No. PIMA534844 Supplier Invitrogen™ Supplier No. MA534844
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Human fetal skeletal muscle tissue.

ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. The SERCA3 gene is not as well characterized and is found in non-muscle cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATP2A1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone JE45-75
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene ATP2A1
Gene Accession No. O14983
Gene Alias adult Ca2+ ATPase; ATP2A; ATP2A1; ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; ATPase, Ca++ transporting, ubiquitous; Ca2+ ATPase; calcium pump 1; Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform; endoplasmic reticulum class 1/2 Ca(2+) ATPase; neonatal Ca2+ ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SERCA; SERCA ATPase; Serca1; SERCA1a; SR Ca(2+)-ATPase 1
Gene Symbols ATP2A1
Host Species Rabbit
Immunogen Synthetic peptide within Human SERCA1 ATPase aa 1-50.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 487
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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