Invitrogen™ ATP4B Recombinant Rabbit Monoclonal Antibody (3Y1Y1)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542699

Catalog No. PIMA542699

Description

Positive test controls include: HT-29, HepG2, Mouse stomach, Rat testis. The target is usually found in the following locations: Cell membrane, Single-pass type II membrane protein. Immunogen sequence: SNGSAPRVDC AFLDQPRELG QPLQVKYYPP NGTFSLHYFP YYGKKAQPHY SNPLVAAKLL NIPRNAEVAI VCKVMAEHVT FNNPHDPYEG KVEFKLKIEK.

The hydrogen/potassium ATPase, or gastric proton pump, belongs to a family of P-type cation-transporting ATPases. This family of ATPases shares a number of functional and structural similarities including the common feature of consisting of an alpha and beta subunit. Like the ubiquitous sodium/potassium ATPase, the hydrogen/potassium ATPase consists of a large transmembrane catalytic subunit, termed the alpha- subunit which contains sites for ATP binding and phosphorylation, and an associated smaller glycoprotein, termed the beta-subunit which may play a role in maintaining the structural and functional integrity of the complex.

Specifications

• Antigen: ATP4B
• Classification: Recombinant Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P18598, P50992, P51164
• Gene Symbols: ATP4B
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 192-291 of human ATP4B (P51164).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 3Y1Y1
• Conjugate: Unconjugated
• Gene: ATP4B
• Gene Alias: (H+,K+)-ATPase beta-subunit; ATP4B; ATP6B; ATPase H+/K+ transporting beta subunit; ATPase H+/K+ transporting subunit beta; ATPase H+K+-transporting beta / (gastric HK-ATPase beta subunit) defined by SSR; ATPase, H+,K+-transporting, beta / (gastric H,K-ATPase beta subunit), defined by SSR; ATPase, H+/K+ exchanging, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide, gastric specific; AV080843; gastric H(+)/K(+) ATPase subunit beta; gastric H+/K+ ATPase beta subunit; gastric H+/K+-ATPase beta subunit; gastric hydrogen-potassium ATPase, beta; gp60-90; H,K-ATPase-Beta; H.K-ATPase, beta subunit; H+,K+-ATPase; H+/K+ ATPase beta; H+/K+ ATPase beta subunit; H+/K+-ATPase beta; H+/K+-ATPase beta subunit; potassium-transporting ATPase beta chain; potassium-transporting ATPase subunit beta; Proton pump beta chain; S76401S1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11945, 24217, 496
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid