Invitrogen™ ATP6V0C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA523972

Catalog No. PIPA523972

Description

This antibody is predicted to react with bovine, canine, equine and rat based on sequence homology.

ATP6V0C is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. ATP6V0C encodes the V0 subunit c.

Specifications

• Antigen: ATP6V0C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATP6V0C
• Gene Alias: Atp6c; Atp6c2; Atp6l; ATP6V0C; ATPase H+ transporting V0 subunit c; ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16 kDa; ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit C; ATPase, H+ transporting, lysosomal 1; ATPase, H+ transporting, lysosomal 16kD, V0 subunit C; ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c; ATPase, H+ transporting, lysosomal 2; ATPase, H+ transporting, lysosomal V0 subunit C; ATPase, H+ transporting, V0 subunit C; ATPL; Atpl-rs1; H(+)-ATPase (mvp); H(+)-transporting two-sector ATPase, 16 kDa subunit; Mvp; PL16; vacuolar ATP synthase 16 kDa proteolipid subunit; vacuolar H+ ATPase proton channel subunit; vacuolar proton pump 16 kDa proteolipid subunit; VATL; V-ATPase 16 kDa proteolipid subunit; Vma3; VPPC; V-type proton ATPase 16 kDa proteolipid subunit
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11984, 527
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P27449, P63082
• Gene Symbols: ATP6V0C
• Immunogen: KLH conjugated synthetic peptide between 100-126 amino acids from the C-terminal region of human ATP6V0C.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG