Invitrogen™ ATP6V0D1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531156

Catalog No. PIPA531156

Description

Recommended positive controls: NT2D1, IMR32, U87-MG. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (94%), Xenopus laevis (95%), Chicken (98%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously.

Specifications

• Antigen: ATP6V0D1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATP6V0D1
• Gene Alias: 32 kd accessory protein; 32 kDa accessory protein; Ac39; AI267038; Atp6d; ATP6DV; Atp6v0d1; ATPase H+ transporting V0 subunit d1; ATPase, H+ transporting, lysosomal (vacuolar proton pump), 42 kDa; ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; ATPase, H+ transporting, lysosomal V0 subunit D1; ATPase, H+ transporting, lysosomal, V0 subunit d1; ATPase, H+ transporting, V0 subunit D; cto; fb73h07; FLJ43534; H(+)-transporting two-sector ATPase, subunit D; lysosomal 38kDa; P39; Physophilin; Unknown (protein for MGC:63769); Vacuolar proton pump subunit d 1; vacuolar proton-ATPase, subunit D; V-ATPase, subunit D; V-ATPase 40 KDa accessory protein; V-ATPase AC39 subunit; V-ATPase subunit d 1; V-ATPase, subunit D; VATX; Vma6; VPATPD; V-type proton ATPa; V-type proton ATPase subunit d 1; wu:fb73h07; zgc:63769
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9114
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P61421
• Gene Symbols: ATP6V0D1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human ATP6V0D1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG