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ATP6V1A Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501569773
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50-156-9773 10 μL
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Catalog No. 50-156-9773 Supplier Bethyl Laboratories, Inc Supplier No. A305193AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Chicken, Bovine, Pig and Orangutan

ATP6V1A encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c′, c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist.

Specifications

Antigen ATP6V1A
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene ATP6V1A
Gene Accession No. P38606
Gene Alias ATP6A1, ATP6V1A, ATP6V1A, ATP6V1A1, ATPase H+ transporting V1 subunit A, HO68, V-ATPase subunit A, VA68, VPP2, Vma1
Gene Symbols ATP6V1A
Host Species Rabbit
Immunogen Between 450 and 500
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 523
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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