Invitrogen™ ATP6V1B2 Polyclonal Antibody

Catalog No.	Quantity
PIPA544549	100 μL

Catalog No. PIPA544549 Supplier Invitrogen™ Supplier No. PA544549

Description

Rabbit Polyclonal Antibody

Peptide sequence: NFIAQGPYEN RTVFETLDIG WQLLRIFPKE MLKRIPQSTL SEFYPRDSAK Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%.

ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.

Specifications

• Antigen: ATP6V1B2
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene: Atp6v1b2
• Gene Accession No.: P21281, P62814
• Gene Alias: AI194269; AI790362; ATP6B1B2; Atp6b2; Atp6v1b2; atp6v1bb; atp6v1bb protein; ATPase H+ transporting V1 subunit B2; ATPase, H transporting, lysosomal V1 subunit B2; ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa, isoform 2; ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B, isoform 2; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; ATPase, H+ transporting, lysosomal V1 subunit B2; ATPase, H+ transporting, lysosomal, V1 subunit B, member b; ATPase, H+ transporting, lysosomal, V1 subunit B2; ATPase, H+ transporting, V1 subunit B, isoform 2; DOOD; endomembrane proton pump 58 kDa subunit; fj51e01; H+ transporting two-sector ATPase; H+-ATPase B subunit; H+-ATPase non-catalytic subunit B; HO57; lysosomal 56/58kDa; R74844; testicular secretory protein Li 65; vacuolar H+-ATPase; vacuolar H+-ATPase 56,000 subunit; vacuolar H+ATPase B2; vacuolar proton pump subunit B 2; vacuolar-type H+ transporting ATPase subunit B2; Vat2; VATB; vatB2; V-ATPase B2 subunit; V-ATPase subunit B 2; Vma2; VPP3; V-type proton ATPase subunit B, brain isoform; wu:fj51e01; zgc:109771; ZLS2
• Gene Symbols: Atp6v1b2
• Host Species: Rabbit
• Immunogen: Synthetic peptide directed towards the middle region of human ATP6V1B2.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11966, 526
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG