ATP7B Mouse anti-Human, Mouse, Rat, Clone: S62-29, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527719
DescriptionThis gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
|PBS with 50% glycerol and 0.09% sodium azide; pH 7.4|
|P35670, Q64446, Q64535|
|ATP7B, ATPase Cu++ transporting beta polypeptide, ATPase Cu(2+) transporting beta polypeptide, Copper pump 2, Copper transporting ATPase 2, PWD, Toxic milk, tx, WC1, WD, Wilson disease associated protein, WND, WND/140 kDa|
|11979, 24218, 540|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot|
|Synthetic peptide amino acids 3-21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2|
|Human, Mouse, Rat|
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