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ATP7B Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984071
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100 μL
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50-198-4071 100 μL
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Catalog No. 50-198-4071 Supplier Bioss Supplier No. BS1718R
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Rabbit Polyclonal Antibody

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Specifications

Antigen ATP7B
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Atp7b
Gene Accession No. P35670
Gene Alias Atp7a; ATP7B; ATPase copper transporting beta; ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease); Copper pump 2; Copper-transporting ATPase 2; Hts; PINA; PINA gene, promoter; pineal night-specific ATPase; PWD; RP11-327P2.1; RP11-327P2.3; toxic milk; tx; WC1; Wd; Wilson disease-associated protein; Wilson disease-associated protein homolog; Wilson protein; Wnd; WND/140 kDa
Gene Symbols Atp7b
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ATP7B.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 540
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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