Atpenin A5, MP Biomedicals™

Description

Mitochondrial Complex II (succinate dehydrogenase or succinate:ubiquinone oxidoreductase) couples the oxidation of succinate to fumarate with the reduction of quinone to quinol. It is a member of the Krebs cycle.

• Highly selective compound, ubiquinone-binding site mitochondrial complex II inhibitor, stimulates mitochondrial channels
• Shows anti-ischemic and cardioprotective effects in vivo
• Used in the Krebs cycle to fumarate with the reduction of quinone to quinol

Specifications

Chemical Identifiers

• CAS: 119509-24-9
• Molecular Formula: C15H21Cl2NO5
• Molecular Weight (g/mol): 366.2, 366.24
• InChI Key: OVULNOOPECCZRG-CIUDSAMLSA-N
• Synonym: FO 125A5, atpenin A5, Antibiotic FO 125A5, Atpenin A5 (Synthetic), (2 S,4 S,5 R)-5,6-Dichloro-1-(2,4-dihydroxy-5,6-dimethoxypyridin-3-yl)-2,4-dimethyl-1-hexanone, (2 S,4 S,5 R)-1-(2,4-Dihydroxy-5,6-dimethoxy-3-pyridinyl)-2,4-dimethyl-5,6-dichloro-1-hexanone, 3-[(2 S,4 S,5 R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1 H)-pyridinone
• IUPAC Name: 3-[(2S,4S,5R)-5,6-dichloro-2,4-dimethylhexanoyl]-2-hydroxy-5,6-dimethoxy-1,4-dihydropyridin-4-one
• SMILES: COC1=C(OC)C(=O)C(C(=O)[C@@H](C)C[C@H](C)[C@@H](Cl)CCl)=C(O)N1

• Quantity: 1 mg
• Melting Point: 83°C to 85°C
• Shipping Condition: -20°C
• Color: White
• Purity: 96.1
• Chemical Name or Material: Atpenin A5

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov