Invitrogen™ Atrophin 1 Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA543943

Catalog No. PIMA543943

Description

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Specifications

• Antigen: Atrophin 1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P54259
• Gene Symbols: ATN1
• Immunogen: Asp879-Leu1190 (Accession P54259), with N-terminal His Tag.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Western Blot
• Clone: C1
• Conjugate: Unconjugated
• Gene: ATN1
• Gene Alias: ATN1; Atr1; atrophin 1; Atrophin1; atrophin-1; B37; D12S755E; dentatorubral pallidoluysian atrophy; dentatorubral-pallidoluysian atrophy protein; Dentatorubral-pallidoluysian atrophy protein homolog; Drpla; HRS; NOD
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 1822
• Content And Storage: -20°C
• Form: Liquid