Invitrogen™ ATXN10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568098

Catalog No. PIPA568098

Description

Predicted to react with Mouse and Rat samples.

The autosomal dominant cerebellar ataxias (ADCAs) are a clinically and genetically heterogeneous group of disorders characterized by ataxia, dysarthria, dysmetria, and intention tremor. All ADCAs involve some degree of cerebellar dysfunction and a varying degree of signs from other components of the nervous system. A commonly accepted clinical classification (Harding, 1993) divides ADCAs into 3 different groups based on the presence or absence of associated symptoms such as brainstem signs or retinopathy. The presence of pyramidal and extrapyramidal symptoms and ophthalmoplegia makes the diagnosis of ADCA I, the presence of retinopathy points to ADCA II, and the absence of associated signs to ADCA III. Genetic linkage and molecular analyses revealed that ADCAs are genetically heterogeneous even within the various subtypes.

Specifications

• Antigen: ATXN10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATXN10
• Gene Alias: AI325283; ataxin 10; ataxin 10 homolog; ataxin-10; ATXN10; Brain protein E46; brain protein E46 homolog; C77170; E46; E46L; HUMEEP; Neuronal beta-catenin-like protein; Sca10; spinocerebellar ataxia 10; spinocerebellar ataxia 10 homolog; spinocerebellar ataxia type 10 protein; Spinocerebellar ataxia type 10 protein homolog; TEG-169; testis expressed gene 169; Tex169
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170821, 25814, 54138
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 30% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P28658, Q9ER24, Q9UBB4
• Gene Symbols: ATXN10
• Immunogen: Synthesized peptide derived from human ATXN10.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG