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Invitrogen™ ATXN10 Polyclonal Antibody
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Catalog No. PIPA5103621
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PIPA5103621 100 μL
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Catalog No. PIPA5103621 Supplier Invitrogen™ Supplier No. PA5103621
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ATXN10.

The autosomal dominant cerebellar ataxias (ADCAs) are a clinically and genetically heterogeneous group of disorders characterized by ataxia, dysarthria, dysmetria, and intention tremor. All ADCAs involve some degree of cerebellar dysfunction and a varying degree of signs from other components of the nervous system. A commonly accepted clinical classification (Harding, 1993) divides ADCAs into 3 different groups based on the presence or absence of associated symptoms such as brainstem signs or retinopathy. The presence of pyramidal and extrapyramidal symptoms and ophthalmoplegia makes the diagnosis of ADCA I, the presence of retinopathy points to ADCA II, and the absence of associated signs to ADCA III. Genetic linkage and molecular analyses revealed that ADCAs are genetically heterogeneous even within the various subtypes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATXN10
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ATXN10
Gene Accession No. P28658, Q9ER24, Q9UBB4
Gene Alias AI325283; ataxin 10; ataxin 10 homolog; ataxin-10; ATXN10; Brain protein E46; brain protein E46 homolog; C77170; E46; E46L; HUMEEP; Neuronal beta-catenin-like protein; Sca10; spinocerebellar ataxia 10; spinocerebellar ataxia 10 homolog; spinocerebellar ataxia type 10 protein; Spinocerebellar ataxia type 10 protein homolog; TEG-169; testis expressed gene 169; Tex169
Gene Symbols ATXN10
Host Species Rabbit
Immunogen A synthesized peptide derived from human ATXN10(Accession Q9UBB4), corresponding to amino acid residues L11-V61.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170821, 25814, 54138
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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